Chapter 1239 Some confidence
“Where did you fail?” Yang Rui wasn’t very nervous, but he was taken aback for a while before continuing to brush his teeth.
Gu Qiang looked ashamed, and said: “The dissociation or purification is not clean, and the image is gray.”
Talking, Gu Qiang rubbed his head vigorously and said: “I have done purification countless times, but I didn’t expect that this time there was a problem.”
“Are all the steps before purification correct?” Yang Rui asked with foam in his mouth.
“It should be no problem, I checked it before.” Periodic inspection is a necessary means, otherwise, the experiment will collapse before the experiment is done later, and the experimenter himself must collapse.
Yang Rui nodded and said, “That way, first, you check yourself to see where the error is.”
Gu Qiang sullen his head and let out an “en”.
“Secondly, I will set up another team to do the inspection for you, mainly to check the experimental records, and compare with your previous experiments to see if there are any differences.” Yang Rui said very atmospherically, which is the scale of his laboratory. If it is too big, otherwise, the existing three repetitive groups will be able to support ordinary scientific research laboratories.
Gu Qiang was still bored, and this time he didn’t say a word.
“Third.” Yang Rui continued: “Your level should be faster. After checking, no matter what the conclusion is, do another set of repetitions. Didn’t I ask you to protect your experimental table before? Consumables There are also records. You can compare them to see if the changes in consumables have caused different experimental results…”
What Yang Rui said is extremely systematic and extremely simple.
is just one sentence in the final analysis, compared with the old foundation left behind.
This is the similarities and differences brought about by whether there is a systematic scientific research experience. Gu Qiang is a semi-wild researcher who has joined the laboratory after graduating from his undergraduate degree. Before that, he felt that Yang Rui’s requirements were cumbersome, and now it is important.
If Gu Qiang still has some doubts about the first and second points, the third point Yang Rui said has more or less boosted Gu Qiang’s mood.
However, Gu Qiang was still a little uneasy and said: “There are so many things in the laboratory, and you can usually not get it wrong.”
“There are so many things that can go wrong. Maybe there is a bottle of medicine that has been released for too long and decomposed in the sun.” Yang Rui casually said an example.
In the laboratory, all brown bottles and black bottles are designed to withstand sunlight. There are more reagents that can be decomposed by ultraviolet rays than people think, especially the solvents currently prepared in the laboratory.
The same principle is also used for bagged marinated chicken drumsticks. If you pay attention, the marinated chicken drumstick bags are opaque. In fact, for sales purposes, allowing consumers to directly see the food inside the packaging bag is the most effective publicity. However, due to the decomposition of sunlight, the beautiful color of the marinated chicken legs will be exposed for a few days. It became pale and pale, and it made people lose their appetite.
There are too many error-prone links in the laboratory, especially for a long series of time, it is even more difficult to make it all at once. Because of this, Yang Rui felt that Gu Qiang’s strong fortune was unbelievable.
did not repeat the success for the first time, in Yang Rui’s view, it was normal.
Gu Qiang curled his eyebrows, waited for Yang Rui to rinse his mouth, wash his face, and walked out of the bathroom, then followed closely, saying: “The problem is, when I do repeated tests, I pay attention to it. I’m worried…”
“There is nothing to worry about.” Yang Rui stopped, turned to look at Gu Qiang, and asked: “The crystal structure has been released. This is the definite evidence. Repeat the experiment, but I want to be cautious, otherwise, I will change to another one. The laboratory, in order to grab time, may have all the articles out now. Therefore, the experiment you did can be repeated. We only need to find out the problem.”
No one has seen the crystal structure of g protein-coupled receptor before.
This is like an image of a rare creature, and it was imaged once with an instrument, which is evidence that iron can no longer be iron.
Gu Qiang silently lowered his head, raised his head again, and whispered: “Are you not afraid of my experiment cheating?”
Yang Rui glanced at him strangely and said, “How could it be an experiment fraud.”
“Do you believe me?” Gu Qiang was suddenly agitated.
“Of course I believe you.” Yang Rui frowned: “What are you worried about.”
Gu Qiang only felt his chest frustrated, and he was speechless.
“Did anyone say anything?” Yang Rui asked.
Gu Qiang nodded slightly and said: “I heard some gossip, it’s nothing.”
After that, he rushed into the bathroom, turned on the faucet, and washed his face well, while washing and blowing his nose, after a while he came out, wiped his face with paper, and said, “It’s okay, I’m just afraid of **** it up. ”
“You have done it, you have done it, and be more confident.” Yang Rui patted Gu Qiang on the shoulder and said: “Okay, don’t think too much, check two more rounds, one repeat experiment, where can it be difficult.”
Gu Qiang clenched his teeth, nodded vigorously, and said, “I will definitely make it.”
“Well, let’s go.”
Yang Rui was still in a state of just waking up, and did not think too much.
He actually forgot. Although he knew the crystal structure of the g protein-coupled receptor made by Gu Qiang, others did not. Even Gu Qiang can’t be sure whether the crystal structure he made is the real crystal structure of g protein-coupled receptor. The second stage is just beginning, and everyone’s knowledge reserves are incomplete.
Even because the solution given by Yang Rui is too one-step in place, everyone’s guess on the crystal structure of the g protein-coupled receptor is not very complete.
Theoretically, Gu Qiang can make the crystal structure of any compound and treat it as a g protein coupled receptor
The crystal structure of the body, the so-called deer is also a horse.
Of course, this kind of fraud is a very low-level fraud, but several of the scientific research frauds that have been exposed in history are high-level. For example, a laboratory in the United States made an AIDS vaccine and injected it into rabbits. It actually produced antibodies. It was a shock to the pharmaceutical industry that year. The result was never repeated and had to admit the fraud. This is a typical mentally retarded fraud, and of course it cannot be repeated. If it can be repeated, doesn’t it mean that the vaccine has succeeded, and it is not called fraud.
In the ion channel laboratory, there are researchers who are familiar with Gu Qiang, and there are assistants who are not familiar with Gu Qiang. In the case of incomplete information, it is inevitable to question Gu Qiang.
In fact, if you look at the schedule on the white wall, you will find that the question is correct-the top foreign laboratory’s progress is not even 1, and Gu Qiang even implemented Yang Rui’s plan in one breath. Extremely unreasonable.
After the initial admiration and shock, everyone’s suspicion followed.
When Gu Qiang has been busy all day and night, but announces repeated failures, some sharp corners are inevitably exposed.
Even Gu Qiang can’t help but doubt himself: Did I make a mistake? Am I wrong? Did I get a specious result by mistake?
Back in the laboratory, Gu Qiang sighed and started a new round of repeated experiments on his own, but his appearance was far from his inner peace.
Yeah!
Horse’s!
This time, before night, Gu Qiang failed again.
Yang Rui heard the sound, went to Gu Qiang’s experiment table and looked at it, and asked: “Operation error?”
“En.” Gu Qiang was extremely annoyed.
“In this way, let’s analyze your last round of experiments first.” Yang Rui said by name, “Professor Man Hai, Professor Tao Xuelin, you are more experienced, um, add Wu Qi, come over, let’s help Gu Qiang analyze .”
Man Hai was obviously a little unhappy, and asked, “How would you like to analyze it?”
“Analyze everything from beginning to end to see the difference between successful and failed experiments.” Yang Rui replied.
Man Hai was surprised: “This will take a lot of time.”
“Perhaps.”
“Should we… don’t bet all the treasures here?” Man Hai couldn’t help but hesitate. He was not familiar with Gu Qiang, so he was unwilling to spend all his precious time here. If it turns out that Gu Qiang’s experiment is problematic, the time spent on a comprehensive analysis may lead the ion channel laboratory to the abyss of failure.
Yang Rui sneered at this, and said: “If you can’t repeat it twice, you have to find a new way? I will give you two years. Can you make a result? Is the plank road so easy to walk?”
What he said was extremely rude, and it could even be said to be a bit critical. As a professor at Peking University, Man Hai was immediately flushed by Yang Rui.
Gu Qiang, who was next to him, also flushed his cheeks.
For him, Yang Rui’s affirmation at this time can be described as nectar.
“Well, a comprehensive analysis, do you find all the different places?” Wu Qi raised his hand cautiously, and by the way, turned away from a somewhat solemn atmosphere.
Yang Rui turned his head and said, “Yes, all the differences must be marked.”
Repeated experiments are not easy experiments. Students who can’t do experiments based on books should feel more about this I have seen one before, I don’t know if it counts. “Wu Qi looked at Yang Rui, and then at Gu Qiang.
Yang Rui and Yan Yue said, “You said.”
Wu Qi swallowed and said, “I read the experimental records of Researcher Gu. The first time he made buffer solution, the isoamyl alcohol was taken from cabinet 3, and the second time he made buffer solution, the isoamyl alcohol was taken from I took it in cabinet 4.”
“What’s the difference? It’s a product of the same company.” Gu Qiang originally had some expectations, but he felt bored at the moment.
His own laboratory table is relatively close to the No. 3 cabinet. After changing the table, it is closer to the No. 4 cabinet. He feels that there is no need to take the reagents in one place.
Wu Qi was a little nervous, and said, “Although it is from the same company, I don’t know if it counts. The isoamyl alcohol in cabinet 4 was sent last month, and it was put here specifically for us to practice. of.”
Gu Qiang’s face suddenly changed: “Why don’t you mark it out?”
Wu Qi whispered: “It’s okay when we use it, but I don’t know if it will affect your experiment.”
“I’ll do it again.” Gu Qiang did not fight with Wu Qi, opened the experimental table, and started to operate.
Everyone spread out, but the topic was still focused on Gu Qiang and his experiments.
……
third more
(End of this chapter)