Chapter 1316 Sense of looking up
“Huh, crystal structure diagram?” Marjorie is a professor of biology at the Caroline School of Medicine, who is not sensitive to words such as g-protein coupled receptors.
What the professors of the Caroline School of Medicine do most is to read the literature, especially the literature of scholars who are eligible for the Nobel Prize.
For them, the Nobel Prize is an advantage and a burden.
The advantage is that the Caroline School of Medicine has received a lot of funding, and the attention of high-end scholars from abroad, the burden is brought by the constant reading of the literature.
The way that professors at Caroline School of Medicine read literature is different from ordinary scholars. Normal people read literature, all they need to read. For example, if Yang Rui wants to read literature, they basically focus on g-protein coupled receptors, pcr, and genes. In short, the fields such as genetics and genetics are what you need to read. Other fields are usually limited to understanding. You can read a few articles at most and just know it.
The professors of the Caroline School of Medicine cannot read the literature like this. They have to read the s-level papers to the end, whether they are in their own field or not, they have to read it, especially the scholars who may win the Nobel Prize. There are also areas where the Nobel Prize may be issued, all of which have to be counted.
A person’s time is limited, and so is the scholar’s time.
Nowadays, in a slightly more popular field, there are three or five laboratories buried in it. The professors of the Caroline School of Medicine spend most of their time reading literature that has nothing to do with their own research. It is conceivable.
For Marjorie, he has gradually become tired of being a professor at the Caroline School of Medicine, but the foundation laid over the years is still there.
Hearing the words “g protein coupled receptor” and “crystal structure diagram”, he was the first to wake up, and hurried to the laboratory.
To be honest, if it weren’t for Yang Rui, he would not believe it.
As professors of biology at the Caroline School of Medicine, Marjorie and their most basic ability is to judge an academic direction, how long will it take to see the light, and how long will it take to see the results.
Of course, such a judgment is definitely inaccurate, but there is also a certain interval.
Yang Rui’s ion channel laboratory has just completed a clear picture of the g protein-coupled receptor-a few months for Wang’s scientific research results, just now-Marjorie believes that the basic time for obtaining the crystal structure diagram is also It should be more than three years, but not more than two years.
Such judgments are not a joke. Whether a laboratory should spend tens of millions of dollars to join such a competition is often based on such judgments:
It is expected that the crystal structure of the g protein-coupled receptor will be revealed in the next two to five years. According to the capabilities of this laboratory, we may complete the project in the next two to four years. There is a certain chance of winning in the relevant competition. Consider joining the competition.
The ion channel laboratory of Peking University completed the crystal structure of the g protein-coupled receptor in a few months, which means that other laboratories around the world that participated in this project are all at a loss.
At the same time, it also means that the resources of the whole society have been greatly saved.
However, what Marjorie cares about is not the saving part. He can’t help feeling nervous when he thinks about the laboratory that is doing related projects.
Other people’s reactions were slower, but they all opened their eyes one after another, and asked hurriedly: “Did you make a clear picture of the crystal structure? So fast?”
“We actually completed the relevant research a few months ago, but it took a relatively long time to repeat the experiment.” Yang Rui said as he let everyone into the laboratory.
In fact, there are not many repeated experiments in a few months. Some verification experiments take a lot of time to do, and they can take several years.
However, Yang Rui’s words fell in the ears of the caring people, but they were as shocking as thunder.
A few months ago, repeated experiments started. When did the results come out?
Dare to believe that in recent months, many laboratories all over the world have been doing wasted work?
Marjorie felt cruel after thinking about it.
However, the scientific research world is so cruel. Those who feel that cruel are dead in the boundless competition, and those who survive can only clenched their teeth.
“Let me see what you have done.” Marjorie asked actively.
Yang Rui smiled and said, “What you see now is the result of repeated experiments. In addition, our paper has also been written.”
The thesis is an experimental record after collation and sublimation, which is naturally the most suitable for reading.
Marjorie didn’t speak much, so he took it and quickly read it.
Behind him, Lanselrot also came from the Catherine College of Medicine, and slowly took a thick paper and read it quietly.
Such papers are very time-consuming to read. Generally speaking, Marjorie is used to skip reading.
But this time, he was a little reluctant.
This is a king-level scientific research project.
It would be wasteful not to look carefully at the papers of the Wang-level scientific research project.
Yang Rui was not in a hurry, greeted people to make tea for them, and sat on the side.
After drinking a few cups of tea, Marjorie finally raised his head and said, “Director Yang, can we talk to the researcher of the specific operation?”
“Of course.” Yang Rui was responsive.
Today is here to show off his skills, but he hesitated for a while when he stood up and shouted: “Gu Qiang, how did you remember?”
“That’s it.” Gu Qiang replied in a low voice.
“Come here, Su Xiankai, Fan Zhenlong…you all come here too.” Yang Rui clicked the names of several people in succession.
“I see the name of Researcher Gu Qiang in the paper.” Marjorie became accustomed to it, and immediately began to trace the completion of the experiment, and asked: “Researcher Gu Qiang, is it convenient to introduce the experiment process?”
Gu Qiang obediently said: “I formed the complex in the presence of detergents? We named this complex the args complex. After testing, I found that it can be effective in the phospholipid bilayer. Coupling…”
“Wait, it is necessary to use detergents. Why do we need to form complexes in the presence of detergents?” Marjorie questioned her first sentence.
Gu Qiang looked at Yang Rui, did not get an answer, shrugged, and said: “Because to ensure the purity of g-protein, detergents are necessary. We want a pure complex, naturally, only in the presence of detergents. get on.”
“Even if the coupling efficiency is greatly reduced?”
“Of course.” Gu Qiang had also studied this issue at the beginning.
However, Marjorie had read more documents than Gu Qiang, and immediately asked: “Have you not considered changing to another method? For example, you do not use detergents, but use physical or other means to ensure g The purity of the protein, I have seen many laboratories are experimenting in this area. How do you make a judgment?”
Gu Qiang opened his mouth, but didn’t know how to answer.
He actually never thought about this problem.
The experimental program Yang Rui gave him was to synthesize in the presence of detergents. Gu Qiang’s theoretical system was weak, and he didn’t even consider circumventing this point.
Of course, his experiment was done too fast, and he quickly broke through this difficulty.
However, Marjorie’s problem is also very typical. Gu Qiang thought for a moment and said honestly: “This was my mission at the time.”
“You mean, did Mr. Yang Rui arrange your plan?”
“Yes.”
Marjorie naturally turned to Yang Rui and asked: “Mr. Yang Rui, how did you think about it at that time?”
“I didn’t think about it.”
“Yep?”
“I arranged for others to try other programs.” Yang Rui calmly said: “Our investment in g-protein coupled receptors is still relatively large.”
Marjorie immediately understood, and said: “Do you have multiple teams trying?”
“Of course. Su Xiankai and Fan Zhenlong were in different groups at the time.” Yang Rui replied in the most concise way.
This is how things are originally.
As the person in charge of the laboratory, Yang Rui proposed a plan and arranged for different researchers to do verification. This is the most basic laboratory operation plan.
It’s like Yang Rui led a march. When encountering a fork in the road, he can certainly decide to stop based on experience and theory, but he can also send people to explore directly.
Fortunately, Gu Qiang found the right direction, nothing more.
In a few simple words, Marjorie knew it well.
He asked Gu Qiang a few more questions, and slowly turned the topic to Yang Rui.
Academic achievements are attributed to IQ for paying and are distributed according to IQ. Hard work itself is worthless.
Yang Rui had questions and answers, and soon established a corresponding image in everyone’s hearts.
As the problem deepened, some scholars began to fail to keep up with the dialogue between Marjorie and Yang Rui, and most people began to concentrate their thoughts on the project itself.
“The Ion Channel Laboratory of Peking University analyzed the crystal structure of the g protein-coupled receptor.”
“Yang Rui’s research is advancing so fast.”
“incredible.”
The whispered discussions of a few people gradually turned into discussions among a group of people.
The fact is that this matter is so shocking that everyone’s questions are repeated.
Marjorie asked questions on his own regardless of what other people thought. From his perspective, understanding Yang Rui now has become a necessary homework.
The g protein-coupled receptor represented by Wang Qi has been broken through by Yang Rui in succession. As long as Marjorie thinks about the sensation that this news can cause, he has to be more careful.
However, while speaking, Marjorie’s mind suddenly appeared in the backyard.
“Mr. Yang Rui, I remember, we seemed to talk about the three-dimensional structure before? Is it the three-dimensional structure of the g protein-coupled receptor? Are you involved in it?” As soon as Marjorie spoke, the surroundings fell silent.
The scholars present seemed to have been reminded, and the expressions on Yang Rui were all wrong.
Think about it, if the repeat experiment of the crystal structure started a few months ago, it means that the main project ended a few months ago. For such a long time, it is impossible for the Ion Channel Laboratory of Peking University to only do repeated experiments. Do new research.
So, new research…
Is the new research the three-dimensional structure of the g protein-coupled receptor?
A group of biologists looked up at Yang Rui, who was tall, with a sense of looking up inexplicably.